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COMPLETE AND COMPREHENSIVE Mixed Connective Tissue Disorder

Mixed Connective Tissue Disorder

What is mixed connective tissue disorder?

Mixed connective tissue disorder is a group of disorders which involve tissues that are protein-rich supporting organs and other body parts. This disorder affects the body parts connecting the body structures. Connective tissues are made of two proteins which are elastin and collagen. It can be genetic or autoimmune. When it comes to the symptoms, they might vary by disease and include pain and fatigue.

The connective tissue examples are cartilage, fat, and bone. This disorder usually comprises the skin, muscles, and joints. It also includes other organ systems which include kidneys, eyes, heart, lungs, gastrointestinal tract, and blood vessels.

Types of connective tissue disorder

There are various types of connective tissue disorders that include:

  • Rheumatoid arthritis
  • Lupus
  • Microscopic polyangiitis
  • Scleroderma
  • Churg-Strauss syndrome
  • Marfan Syndrome
  • Polymyositis/Dermatomyositis

Symptoms of connective tissue disorder

The early mixed connective tissue disorder symptoms are listed below:

  • Unwell feeling- Fatigue and a mild fever
  • Swollen fingers or hands
  • Muscles and joint pain
  • Red rashes
  • Cold and numb fingers

Causes of mixed connective tissue disorder

Mixed connective tissue disorder is usually caused by family genetics and doctors consider it a heritable connective tissue disorder. There are non-inherited causes of mixed connective tissue order which include:

  • Infections
  • Ultraviolet light exposure
  • Exposure to toxic chemicals like cigarette smoke and air pollution
  • Not consuming proper nutrition such as vitamins C and D

Diagnosis of mixed connective tissue disorder

The doctor might order several tests depending on the symptoms of connective tissue disorder and the type of disorder that’s detected. The doctor asks for the patient’s medical history, and family history, and initiates a physical evaluation. Following are the tests which might be needed to confirm the condition:

  • Imaging tests like Magnetic resource imaging scans (MRI) and X-rays
  • Antibodies tests, primarily for autoimmune conditions
  • Tests for dry eyes and mouth
  • Tissue biopsy
  • Blood tests
  • Urine tests
  • Tests for inflammation markers, such as erythrocyte sedimentation rate (ESR) and C-reactive protein

Treatment for mixed connective tissue disorder

Currently, there is no cure available for mixed connective tissue disorder treatment. However, certain medications are recommended to manage the symptoms. The following are the usually recommended medication options:

  • Corticosteroids- Helps prevent the immune system from attacking healthy cells and suppressing inflammation.
  • Calcium channel blockers- Assists in relaxing the muscles in the blood vessel walls and are used for treating Raynaud’s phenomenon (decreased blood flow to the fingers).
  • Pulmonary hypertension medications like Bosenton and sildenafil are prescribed
  • Antimalarial drugs- Helps to treat mild disorders and avert flare-ups
  • Other immunosuppressants- Other medications recommended depending on the signs of the patient

Why should you choose BM Birla Heart Research Centre for the treatment of mixed connective tissue disorder?

BM Birla Heart Research Centre is a state-of-the-art cardiac hospital delivering exceptional heart care services for decades. BMBHRC is the only cardiac centre in eastern India endeavouring to form a superlative cardiac care delivery system, synergizing clinical skills with empathetic patient care.

The dynamic and highly qualified cardiac specialists ensure to put their best efforts to offer their finest services. We deliver a comprehensive range of medical, interventional, and surgical care. Here are some of the strengths which is why you must get in touch with us for the treatment of connective tissue disorder:

  • NABH-Accreditation
  • Economical, ethical and compassionate services  
  • Our labs are well equipped with advanced equipment and cardiac machines
  • Team of cardiac care professionals
  • Adhere to international standards and protocols


Can connective tissue disorders be prevented?

Yes, it can be prevented by eating healthy food containing the required vitamins and nutrition. You must avoid exposure to toxins and chemicals to prevent the risk of connective tissue disorder.

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