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Bradykinesia: Definition, Symptoms, and Treatment

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Bradykinesia: Definition, Symptoms, and Treatment

Neurosciences | Posted on 09/04/2024 by Dr. Amit Chakrabarty



Introduction 

Imagine trying to straighten your arm while simultaneously flexing your biceps. Movement is difficult and delayed due to the tension created by the conflicting messages. Picture this same feeling travelling down your legs as you walk; no matter how hard you try to relax, every step seems painful. This difficulty in initiating and regulating movement provides an insight into the everyday struggles faced by people with bradykinesia. 

Bradykinesia is a primary symptom of Parkinson's disease and other neurological disorders that significantly impair a person's mobility and quality of life. The phrase is derived from the Greek words "bradys," which means sluggish, and "kinesis," which means movement. One well-known example of bradykinesia is the renowned boxer, Muhammad Ali. In the 1980s, Ali was diagnosed with Parkinson's disease, and one of the main symptoms he experienced was bradykinesia. His motor abilities were greatly damaged by the bradykinesia-associated slowness of movement, which made it difficult for him to do even basic chores. His story significantly increased public awareness of the illness and provided support for ongoing research and treatment initiatives. If you are having any of the symptoms, don’t hesitate to schedule an appointment with one of the best neurologist in Jaipur at CK Birla Hospitals. 

What is Bradykinesia?

Bradykinesia is a clinical symptom that is characterised by a notable reduction in the speed and amplitude of physical motions, including slowness of voluntary movements. It is a main characteristic of neurological diseases such as Parkinson's disease, where it shows up as trouble beginning and completing motions, greatly impairing daily activities. Bradykinesia is characterised by a delay in initiating movements and a progressive slowing down of continuing motions. It is also frequently associated with a decrease in facial expressions and a decline in fine motor skills. It is indicative of a fundamental malfunction in the dopaminergic motor control circuits of the brain.

What Are the Symptoms of Bradykinesia?

Bradykinesia is a primary symptom of Parkinson's disease and other neurological illnesses that predominantly affects many parts of everyday living due to a noticeable slowness in voluntary movement. 

The primary symptoms are as follows:

  • Hypokinesia or slowness of movement: It is determined by difficulty starting motions and a decrease in the amplitude and speed of physical acts.
  • Impaired Fine Motor Skills: Difficulties with precision-based tasks, like writing or buttoning clothing, frequently result in micrographia, or small, cramped handwriting.
  • Reduced Facial Expressiveness: A "masked face" with fewer unplanned facial expressions, such as fewer blinks.
  • Difficulty Performing Routine Actions: Issues with basic motions such as walking, turning in bed, or getting out of a chair.

What are the Causes of Bradykinesia?

Usually, neurological disorders that affect the brain's motor control pathways, especially those involving dopamine cause bradykinesia. Among the primary reasons are:

  • Parkinson's disease is the most common cause of motor symptoms, including bradykinesia, due to a progressive loss of dopamine-producing neurons in the substantia nigra.
  • Bradykinesia is also a complication of other neurodegenerative disorders, such as multiple system atrophy, progressive supranuclear palsy, and Huntington's disease.
  • Bradykinesia can be brought on by or made worse by some medications, particularly antipsychotics and antiemetics that block dopamine transmission.

What are the Risks and Complications of Bradykinesia?

Bradykinesia carries several hazards and problems that might impact one's physical and mental health. Important complexities consist of:

  • Increased Fall Risk: Instability caused by slowness and difficulties moving about can increase the chance of falls and the damage they cause.
  • Loss of Independence: Being unable to carry out routine tasks on one's own might result in a loss of autonomy and the need for help with everyday duties.
  • Dysphagia, or difficulty swallowing: Bradykinesia can impair the muscles that are used for swallowing, increasing the possibility of aspiration and the respiratory infections that may follow.
  • Emotional and Psychological Impact:Depression and anxiety may be exacerbated by the difficulties caused by bradykinesia, such as social disengagement.

How is Bradykinesia Diagnosed?

A neurologist will perform a thorough clinical evaluation to diagnose bradykinesia, with an emphasis on movement and associated symptoms. Usually, the diagnosis consists of:

  • Clinical Observation: Evaluation of other Parkinsonian characteristics include rigidity and tremor, as well as the slowness and diminished amplitude of voluntary movements.
  • Medical History: A complete examination of the patient's past health, encompassing any neurological disorders or symptoms.
  • Imaging Research: While MRI or PET scans are not usually necessary for the diagnosis of bradykinesia per se, they can be utilised to rule out other possible explanations of symptoms.
  • Movement Scales: The assessment of the intensity of motor symptoms using standardised measures such as the Unified Parkinson's Disease Rating Scale (UPDRS).

What are the Treatment Options for Bradykinesia?

The goals of bradykinesia treatment are to enhance quality of life by controlling the underlying neurological disorder and reducing symptoms. The main forms of treatment consist of:

  • Medication: The most successful form of treatment is levodopa replacement therapy, which is frequently enhanced and prolonged by the addition of dopamine agonists or MAO-B inhibitors.
  • Physical Therapy: To preserve strength, balance, and mobility as well as to lessen the consequences of bradykinesia, regular exercise and physiotherapy are essential.
  • Occupational therapy: Offers techniques and resources to increase independence and safety while assisting people in adjusting to daily responsibilities.
  • Surgical Interventions: Deep brain stimulation (DBS) is a possibility in more advanced instances to control brain activity and enhance motor performance.

Conclusion

Bradykinesia is a difficult and significant symptom that is typically connected to neurological conditions such as Parkinson's disease. Because of its impact on mobility, day-to-day activities, and general quality of life, early diagnosis and thorough treatment are crucial. It is possible to control the symptoms and preserve independence by combining medicine, physical therapy, and, in certain situations, surgical procedures. People with bradykinesia can manage the intricacies of the condition, maintaining their health and improving their quality of life, with continued medical assistance, individualised care, and a proactive approach.

FAQs


What is bradykinesia?

A neurological condition called bradykinesia is determined by sluggish voluntary movements. It frequently affects people who have Parkinson's disease, making it challenging to start and carry out daily tasks including dressing, writing, and walking. The quality of life and motor control are greatly affected by bradykinesia. 

Why does bradykinesia occur?

A lack of dopamine in the brain, specifically in the basal ganglia, which controls movement, results in bradykinesia. It is most frequently linked to Parkinson's disease, in which the distinctive slowness of movement results from a progressive loss of dopamine-producing neurons.

Can bradykinesia cure itself?

Bradykinesia does not typically resolve on its own, as it is usually associated with chronic neurological conditions like Parkinson’s disease. While it cannot be cured, symptoms can be managed with medications, physical therapy, and lifestyle modifications to improve mobility and quality of life.

How to test for bradykinesia?

Testing for bradykinesia involves a clinical evaluation by a neurologist, focusing on movement speed and initiation. The Unified Parkinson’s Disease Rating Scale (UPDRS) is often used to assess severity. Imaging studies like MRI or PET scans may help rule out other conditions but are not directly used to diagnose bradykinesia.